Publications

Extracellular-signal regulated kinase 8 of Trypanosoma brucei uniquely phosphorylates its proliferating cell nuclear antigen homolog and reveals exploitable properties. Valenciano A, Knudsen GM, Mackey ZB. Cell Cycle 2016; 15(20):282640.                  

Deviating the level of proliferating cell nuclear antigen in Trypanosoma brucei elicits distinct mechanisms for inhibiting proliferation and cell cycle progression. Valenciano A, Ramsey A, Mackey, ZB. Cell Cycle 2015; 14:4, 674-688, doi: 10.4161/15384101.2014.987611 

Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei. Sanchez LM, Knudsen GM, Helbig C, De Muylder G, Mascuch SM, Mackey ZB, Gerwick L, Clayton C, McKerrow JH, Linington RG. J Nat Prod. 2013 Apr 26;76(4):630-41. doi: 10.1021/np300834q. Epub 2013 Feb 27

Early invasion of brain parenchyma by African trypanosomes. Frevert U, Movila A, Nikolskaia OV, Raper J, Mackey ZB, Abdulla M, McKerrow J, Grab DJ. PLoS One. 2012;7(8):e43913. doi: 10.1371/journal.pone.0043913. Epub 2012 Aug 31.

Antitrypanosomal and cysteine protease inhibitory activities of alkyldiamine cryptolepine derivatives. Lavrado J, Mackey Z, Hansell E, McKerrow JH, Paulo A, Moreira R. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6256-60. doi: 10.1016/j.bmcl.2012.07.104. Epub 2012 Aug 15.